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Ingredient Evidence Review

L-Citrulline in Nitric Boost Ultra

Detailed review of L-citrulline DL-malate in Nitric Boost Ultra, human evidence, arginine availability, studied doses and formulation limitations.

Desk ResearchEvidence LabelsSafety ContextUpdated Aug 2026
L-Citrulline in Nitric Boost Ultra visual
Why it is included

L-citrulline can contribute to circulating arginine availability.

L-citrulline is converted in the body to L-arginine. This gives it an indirect but meaningful connection to nitric-oxide synthesis. Oral citrulline also avoids some of the immediate metabolism that affects oral arginine, which is why it is frequently investigated in vascular and exercise contexts.

A small human study involving men with mild erectile dysfunction used 1.5 g/day L-citrulline and reported improvement in erection-hardness score among some participants. The study was small and should be interpreted as preliminary rather than definitive.

Nitric Boost Ultra lists L-citrulline DL-malate. A study using pure L-citrulline cannot automatically be mapped gram-for-gram onto a citrulline-malate ingredient without knowing the composition and dose.

Nitric Boost Ultra product visual for L-citrulline evidence page
Evidence grade

Promising mechanism, limited direct clinical depth.

Mechanism

Credible: citrulline can raise arginine availability and thereby support nitric-oxide synthesis.

Human evidence

Preliminary: small studies exist, but the evidence base is not large enough for strong universal conclusions.

Product relevance

Uncertain without a verified dose and composition for the citrulline-malate ingredient.

Formulation detail

Why “citrulline malate” deserves separate attention.

Commercial citrulline-malate ingredients can differ in the ratio of citrulline to malate. The total mass of a blend is therefore not always equal to the amount of actual citrulline. This matters when a research paper reports a dose of pure L-citrulline.

Without composition information, MPS does not state that Nitric Boost Ultra supplies a research-matched citrulline dose.

See how citrulline fits the nitric-oxide pathway →

MPS assessment

Useful evidence-linked ingredient, but not finished-product proof.

L-citrulline strengthens the biological rationale of the formula. It should still be described as an ingredient with preliminary human relevance rather than evidence that Nitric Boost Ultra itself is clinically proven.

Selected references

Research trail

  1. Rhim HC, Kim MS, Park YJ, et al. Arginine supplements and erectile dysfunction: systematic review and meta-analysis. PubMed PMID 30770070.
  2. Cormio L, De Siati M, Lorusso F, et al. Oral L-citrulline supplementation in men with mild erectile dysfunction. PubMed PMID 21195829.
  3. Xu Z, Liu C, Liu S, Zhou Z. L-arginine and PDE5 inhibitors in erectile dysfunction: systematic review/meta-analysis. PubMed PMID 33587304.
  4. D'Aniello G, et al. D-aspartic acid and testosterone: systematic review. PubMed PMID 28280794.
  5. Current merchant/product materials supplied for this project, reviewed August 21, 2026. Product formulation, prices, bonuses and guarantee statements are treated as merchant representations rather than independent efficacy evidence.

References are included for research context. Evidence on a constituent ingredient does not automatically validate the finished product.

Current merchant offer

Compare the current Nitric Boost Ultra package options.

The supplied merchant materials reviewed August 21, 2026 show one-, three- and six-jar packages. Commercial terms can change; verify the live checkout before purchasing.

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